承担国家科技支撑计划1项，省部级课题1项，局级课题5项，发表论文20余篇，其中SCI论文收录9篇，第一作者5篇，累计影响因子23.5。参编著作2部。承担药物及器械临床试验20余项，研究内容包括新药与器械临床转化，糖尿病中西药研究等方面。
主持科研项目：
1. 四大慢病国家重大项目：重大慢病数智驱动全链条防控技术范式的示范与推广研究 2024.12-2028.12 课题负责人 主持 经费3100万。
2. 首都卫生发展专项“索利那新联合葛根治疗膀胱过度活动症增效减毒研究” 2024-2027年 主持 经费40万
3. 临床试验项目、中心课题4项。
所获成果：（包括科研成果奖、专利、专著等）
1.《康复照护师》副主编 青岛出版集团
2.《老年康养政策与法规》主编 北京出版社
代表性文章：
(1) Jingyi Li , Yixin Xing , Wei Gu , Shousi Lu * Biomimetic mineralization engineered phycocyanin with improved stability and antioxidantive activity under environmental stress.Materials Letters 356 (2024) 135576.[IF=3.0]
(2) Yixin Xing, Jingyi Li, Yuanjie Fan , Shousi Lu,* , Wei Gu*. Coordination of iron ions with phycocyanin for an improved Fenton activity at weakly acidic pH. Spectrochimica Acta Part A.Molecular and Biomolecular Spectroscopy 310 (2024) 123975. [IF=4.83]
(3) Xinyue Jia Yixin Xing Yuanjie Fan Wei Gu and Shousi Lu Mitigating the adverse effect of pH on stability and antioxidant activity of phycocyanin via nanohydrogel encapsulation. Functional Materials Letters (2024) 2450021.
(4) Lu SS, Guo S, Xu P, Li X, Zhao Y, Gu W, Xue M Hydrothermal synthesis of nitrogen-doped carbon dots capable of cellular imaging and blood-brain barrier crossing. Int J Nanomedicine. 2016 28,(11):6325-6336.(IF=4.32)
(5)Lu SS, Yu YL, Liu XD, Liu L, Liu YW, et al. Berberine promotes glucagon-like peptide-1 (7–36) amide secretion in streptozotocin-induced diabetic rats. J Endocrinology 2009; 200：159–65. [IF=5.2]
(6) Qunying Chen, Lu Bai, Xuelin Zhou, Pingxiang Xu,Xiaorong Li, Huanli Xu,Yuanyuan Zheng, Yuming Zhao, Shousi Lu* and Ming Xue. Development of long-circulating lapachol nanoparticles: formation, characterization, Pharmacokinetics, distribution and cytotoxicity.RSC Advances. 2020, 10, 30025 [IF=3.8].
(7) Haiting Cheng*, Can Cui*,Lu ss* et al Identification and analysis of hub genes and net works related to hypoxia preconditioning in mice. Oncotarget 2017. 9(15): 11889-11904（IF=5.1）
(8) Guo S, Lu SS, Xu P, Ma Y, Zhao L, Zhao Y, Gu W, Xue M Biomimetic synthesis of needle-like fluorescent calcium phosphate/carbon dot hybrid composites for cell labeling and copper ions detection. Dalton Trans. 2016 4;45(18):7665-71 [IF=4.0]
(9) Yu YL, Lu SS, Yu S, Liu YC, Wang P, Xie L, et al. Huang-Lian-Jie-Du decoction modulates glucagon-like peptide 1 secretion in diabetic rats. J Ethnopharmacology 2009; 124：444–449. [IF=3.0]
(10) Liang Y, Liu L, Luss, Wang GJ et al. Application of a hybrid ion trap/time-of-
flight mass spectrometer in metabolite characterization studies: structural identification of the metabolism profile of antofloxacin in rats rapidly using MS information and accurate mass measurements. J Pharm Biomed Anal. 2009; 50(5):1022-1025.
(11)Y Liu, H Liu, J. Yang, XD Liu, Lu SS.T.Wen, L.Xie and G.J Wang. Increase amyloid-peptide (1-40) level in brain of STZ induced diabetic rats. Neuroscience 2008；153，796–802.
(12)Liu L, Deng Y, Yu S, Lu SS, Xie L & Liu XD. Berberine attenuates intestinal disaccharidases in STZ-induced diabetic rats. Pharmazie. 2008；63：384-388.
